neurotrophic corneal ulcer after topical tetracaine abuse: management guidelines

Neurotrophic Corneal Ulcer after Topical Tetracaine Abuse: Management Guidelines

Dear Editor, Indeed, topical ocular anesthesia has been part of modern ophthalmology for more than a century. All forms of anesthetics can be toxic, particularly when abused. In Iran, the most common topical anesthetic is tetracaine. Most of the patients abuse it after UV keratitis or foreign body removal. The ocular surface and cornea are the most common sites of such toxicity. Systemic side e...

Treatment of Acanthamoeba neurotrophic corneal ulcer with topical matrix therapy

BACKGROUND This study was done to evaluate the visual and anatomical outcomes of topical regenerating agents as a novel therapy for neutrophic corneal ulcer (NCU) secondary to acanthamoeba infection. FINDINGS A 20-year-old woman with a history of contact lens wear was referred to our hospital for keratitis after responding poorly to conventional treatment. In vivo confocal microscopy images s...

[Neurotrophic corneal ulcer in an HIV patient].

CASE REPORT We present the case of a 29 year-old man who came to the Emergency Department due to pain in the right eye. There was demonstrated a complete corneal de-epithelialisation. There was no clinical improvement after appropriate treatment, which was complicated by migraine and vomiting. The computerized tomography (CT) scan showed images suggestive of cerebral toxoplasmosis. After the co...

persistent corneal epithelial defect as a complication of tetracaine abuse

purpose: to describe the clinical signs, diagnosis and treatment of toxic keratopathy in a patient who abused tetracaine drops. case report: a 32-year-old man was referred to the emergency ward of our center with persistent corneal epithelial defect associated with a ring infiltrate in the corneal stroma, without any history of ocular trauma or contact lens use. the patient was hospitalized and...

Role of Topical Ascorbic Acid in Management of Refractory Corneal Ulcer

Ascorbic acid, a water soluble vitamin, helps in collagen assembly, synthesis of neurotransmitters, has immune functions and also acts as a major antioxidant in the body. Refractory corneal ulcer is a challenging situation faced by every ophthalmologist in developing countries. Available treatment options for refractory corneal ulcer are bandage contact lens, grid keratotomy, therapeutic penetr...

Challenges in the management of corneal ulcer.